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Oncometabolites in cancer aggressiveness and tumour repopulation

Emerging sources such as microplastics and electronic waste further complicate the regional scenario

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The active metabolite of folate, 5-methyltetrahydrofolate (5-MTHF, L-methylfolate), participates in re-methylation of the amino acid metabolite homocysteine, creating methionineThere are few intervention studies of folic acid or 5-MTHF as a stand-alone treatment for depression related to folate deficiency